Contributions to Books/Reviews
1. Zachau, H.G., Dütting, D., Melchers, F., Feldmann, H., Thiebe, R.: On serine-specific transfer ribonucleic acids. Symp. Federation European Biochemical Societies, Vienna, p. 21, Pergamon Press, Oxford, 1965.
2. Melchers, F.: The N-terminal amino acid sequence in a k-type mouse light chain. FEBS-Symposium, Vol. 15, Prague, pp. 169-175, 1969.
3. Melchers, F.: Symposium der deutschen Forschungsgemeinschaft über Glykosaminoglykane und Glykoproteine, Bochum, 1968. Hoppe-Seyler's Z. Physiol. Chem., 350:670, 1969.
4. Melchers, F.: The structure, genetics and formation of antibodies. The carbohydrate composition of a myeloma protein from different subcellular fractions of plasma cells. Behr. Mitt. 49:169-183, 1969.
5. Antibody Workshop Meeting, Kronberg, Taunus, Germany, 1969.
6. Melchers, F.: Die Bildung von Antikörpern. Umschau in Wissenschaft und Technik, Heft 4, S. 105, 1969.
7. Messer, W., Melchers, F.: The activation of mutant ß-galactosidase by specific antibodies. In: "The Lactose Operon," ed. D. Zipser, Cold Spring Harbor Monographs, p. 305, 1970.
8. Melchers, F.: Biosynthesis, transport and secretion of immunoglobulin in plasma cells. Histochem. J. 3:389-397, 1971.
9. Melchers, F., Köhler, G., Messer, W.: Stabilization of conformations of Escherichia coli beta-galactosidase by specific antibodies.In: 23rd Mossbach Colloquium of the Germany Society for Biological Chemistry on Protein-Protein Interactions, pp. 409-425, Springer, Berlin, 1972.
10. Melchers, F.: Synthesis, transport and secretion of immunoglobulins. "Immunoglobulins," pp. 49-59, North Holland, Amsterdam, 1972.
11. Melchers, F.: Synthesis, transport and secretion of immunoglobulin in lymphoid cells. In: "Biochemistry of Gene Expression in Higher Organisms," Sydney, eds. J.K. Pollak, J.W. Lee, pp. 542-554, Australia and New Zealand Book Co., Sydney, 1973.
12. Melchers, F.: Possible roles of the carbohydrate groups in biological functions of the glycoproteins, immunoglobulin M and G. In: "Int. Symp. Membrane-mediated Information," Oxford 1972, ed. P.W. Kent, Vol. 2, pp. 39-56, MTP, Lancaster, 1973.
13. Melchers, F., Andersson, J.: Secretion of immunoglobulins. Adv. Cytopharm. 2:225-235, 1974.
14. Melchers, F., Andersson, J.: Proliferation and maturation of bone marrow-derived lymphocytes. In: "Cellular Selection and Regulation in the Immune Response," ed. G.M. Edelman, pp. 217-231, Raven Press, New York, 1974.
15. Andersson, J., Melchers, F.: The differentiation of B cells by mitogens. In: "Progress in Immunology II," eds. L. Brent, J. Holborow, pp. 127-135, North-Holland, Amsterdam and American Elsevier, New York, 1974.
16. Melchers, F.: Lymphocyte membranes in lymphocyte functions. In: "Perspectives in Membrane Biology," eds. S. Estrada-O., C. Gitler, pp. 531-558, Academic Press, New York, 1974.
17. Melchers, F., Andersson, J.: Immunoglobulin production in B-lymphocytes: synthesis of the membrane-bound receptor and the secreted serum glycoprotein immunoglobulin M. Biochem. Soc. Symp., 40:73-85, 1974.
18. Melchers, F., Lafleur, Anderson, J.: Immunoglobulin M synthesis in resting (Go) and in mitogen-activated B-lymphocytes. In: "Control of Proliferation in Animal Cells", Cold Spring Harbor Laboratory, pp. 393-410, 1974.
19. Melchers, F.: Changes in receptor immunoglobulin turnover during B-lymphocyte differentiation. In: "Molecular Aspects of Membrane Phenomena," eds. H.R. Kaback et al., pp. 64-72, Springer-Verlag, Berlin, 1975.
20. Melchers, F.: Biochemical characterization of immunoglobulin-producing B-lymphocytes at different stages of their differentiation.In: "Regulation of Growth and Differentiated Function in Eukaryotic Cells," eds. P. Talwar, B. de Monte, pp. 229-234, Raven Press, New York, 1975.
21. Andersson, J., Melchers, F.: Lymphocyte stimulation by Con A. In: "Concanavalin A as a Tool," eds. H. Bittiger, H.P. Schnebli, pp. 505-522, J. Wiley and Sons, London, 1976.
22. Melchers, F.: Immunoglobulin synthesis and mitogen reactivity: markers for B lymphocyte differentiation. In: "Development of Host Defenses," eds. M.D. Cooper, D.H. Dayton, pp. 11-29, Raven Press, New York, 1977.
23. Andersson, J., Melchers, F.: Mitogen stimulation of B lymphocytes. A mitogen receptor complex which influences reactions leading to proliferation and differentiation. In: Cell Surface Reviews 3:601-618, 1977.
24. Melchers, F.: T-cell hybrids: shortcut or dead end? Nature 271:9-10, 1977.
25. Phillips, R.A., Melchers, F., Miller, R.G.: Stem cells and the ontogeny of B lymphocytes. Progr. Immunol. Vol. III, 155-161, 1977 .
26. Melchers, F., Pernis, B., Krolick, K.A.: Membranes and signalling. In: "Regulation of the Immune System: Genes and the Cells in which They Function," Vol. VI, eds. E. Sercarz, L. Herzenberg, F. Fox, pp. 747-752, Academic Press, New York, 1977.
27. Melchers, F.: Receptors for the regulation of growth and differentiation of murine B-lymphocytes. In: "Regulations of Membrane Origin," eds. P. Guerrier, N. Moreau, Biologie Cellulaire 32:9-18, 1978.
28. Melchers, F., Potter, M., Warner, N.L.: Preface to "Lymphocyte Hybridomas". Curr. Topics Microbiol. Immunol. 81, IX XXIII, 1978.
29. Melchers, F.: B-lymphocyte development and growth regulation. In: "Differentiation of Normal and Neoplastic Hematopoietic Cells," eds. B. Clarkson, P.A. Marcks, J.E. Till, Cold Spring Harb. Conf. Cell Prolif. 5:485-503, 1978.
30. Andersson, J., Coutinho, A., Melchers, F.: The role of immunoglobulin in the induction of B-lymphocytes. In: "Cells of Immunoglobulin Synthesis" eds. B. Pernis, H.J. Vogel, pp. 209-221, Academic Press, New York, 1979.
31. Melchers, F.: Synthesis and processing of immunoglobulins. In: "Processing and Turnover of Proteins and Organelles in the Cell", eds. S. Rapoport, T. Schewe, FEBS 12th Meeting Dresden 1978, Vol. 53, pp. 57-69, Pergamon Press, Oxford & New York, 1979.
32. Andersson, J., Coutinho, A., Lernhardt, W., Melchers, F.: B cell triggering. In: "B Lymphocytes in the Immune Response," eds. M. Cooper, D. Mosier, I. Scher, E.S. Vitetta, pp. 257-262, Elsevier/North Holland, Inc., New York, 1979.
33. Melchers, F.: Discussions on triggering and tolerance in B-cells. In: "B Lymphocytes in the Immune Response," eds. M. Cooper, D. Mosier, I. Scher, E.S. Vitetta, pp. 271-274, Elsevier/North Holland Inc., New York, 1979.
34. Melchers, F.: Three waves of B lymphocyte development during embryonic development of the mouse. In: "Cell Lineage, Stem Cells and Cell Determination," ed. N. Le Douarin, pp. 281-288, Elsevier/North-Holland Biomed. Press, Amsterdam, 1979.
35. Melchers, F.: Organization of immunoglobulin synthesis. In: "Cell Compartmentation and Metabolic Channeling," eds. F. Nover, F. Lynen, K. Mothes, pp. 447-452, G. Fischer-Verlag, Jena, 1980.
36. Melchers, F., Andersson, J.: Different qualities of B lymphocyte mitogens. In: "Microbiology 1980," American Society for Microbiology, pp. 16-18, 1980.
37. Melchers, F., Andersson, J., Lernhardt, W., Schreier, M.H.: Functional studies on receptor complexes of B lymphocytes involved in regulation of growth and maturation. In: "The Lymphocyte Cell Surface," eds. P.B. Garland, M.J. Crumpton, pp. 75-88, The Biochemical Society, London, 1980.
38. Melchers, F.: Interactions of bacteria with the immune system. In: "The Molecular Basis of Microbial Pathogenicity," eds. H. Smith, J.J. Skehel, M.J. Turner, pp. 285-305, Verlag Chemie, Weinheim, West Germany, 1980.
39. Melchers, F.: T cell-dependent B cell stimulation in the mouse. In: "Primary Immunodeficiencies," eds. M. Seligmann, W.H. Hitzig, pp. 173-177, Elsevier/ North Holland Biomedical Press, Amsterdam, 1980.
40. Melchers, F.: Theme 3: Summary. Expression of Antigen Receptors in Lymphocytes and Cellular Activation Mechanisms," Prog. Immunol. 4:202-206, 1980.
41. Melchers, F., Andersson, J., Lernhardt, W., Schreier, M.H.: Roles of surface bound immunoglobulin molecules in regulating the replication and maturation to immunoglobulin secretion of B lymphocytes. Immunol. Rev. 52:89-114, 1980.
42. Andersson, J., Melchers, F.: T cell-dependent excitation and stimulation of B cells. In: "B Lymphocytes in the Immune Response," eds. N. Klinmann, D.E. Mosier, I. Scher, E.S. Vitetta, pp. 307-314, Elsevier/ North Holland, New York, 1981.
43. Melchers, F., Andersson, J., Lernhardt, W., Schreier, M.H.: Cellular interaction and the environment in lymphocyte development: the roles of antigen, histocompatibility, and growth factors in T cell-dependent B cell stimulation. In: "Control of Cellular Division and Differentiation," eds. D. Cunningham, E. Goldwasser, J. Watson, C.F. Fox, pp. 579-588, A. Liss, Inc., New York, 1981.
44. Melchers, F., Andersson, J.: T cell dependent regulation of antibody by B cells. In: "The Menarini Series on Immunopathology," Vol. 3, Immunogenetics, eds. L. Bolis, G. Torrigiani, pp. 19-22, 1981.
45. Melchers, F., Andersson, J.: Exciting B cells. In: "The Immune System. Festschrift in Honor of Niels Kaj Jerne on the Occasion of his 70th Birthday," Vol. I, eds. C.M. Steinberg, I. Lefkovits, pp. 124-131, Karger, Basel, 1981.
46. Melchers, F.: Continuously growing lines and clones of antigen-committed T- and B-lymphocytes. In: "Biological Products for Viral Diseases," ed. P.A. Bachmann, pp. 173-180, Taylor and Francis Ltd., London, 1981.
47. Melchers, F.: Introduction. In: "Basel Institute for Immunology Annual Report 1980", Basel Institute for Immunology, pp. 1-18, 1981.
48. Melchers, F., Andersson, J., Corbel, C., Leptin, M., Lernhardt, W., Gerhard, W., Zeuthen, J.: Regulation of B lymphocyte replication and maturation. J. Cell. Biochem. 19:315-332, 1982.
49. Melchers, F.: How to produce antigen-specific antibodies in tissue culture. J. Cell. Physiol. Suppl. 2:107-116, 1982.
50. Melchers, F.: Introduction. In: "Basel Institute for Immunology Annual Report 1981", Basel Institute for Immunology, pp. 1-11, 1982.
51. Melchers, F., Corbel, C., Leptin, M., Lernhardt, W., Zeuthen, J., Andersson, J., Gerhard, W.: B cell activation. In: "Humoral Factors in Host Defense", eds. Y. Yamamura, H. Hayashi, T. Honjo, T. Kishimoto, M. Muramatsu, T. Osawa, pp. 45-59, Academic Press, New York, 1983.
52. Melchers, F., Corbel, C., Leptin, M.: Requirements for B-cell stimulation. In: "Progress in Immunology", Vol. 5, eds. Y. Yamamura, T. Tada, pp. 669-682, Academic Press Japan, Inc., Tokyo, 1983.
53. Melchers, F., Corbel, C.: Studies on B-cell activation in vitro. Ann. Immunol. (Inst. Pasteur) 134D:63-73, 1983.
54. Melchers, F.: Introduction. In: "Basel Institute for Immunology Annual Report 1982", Basel Institute for Immunology, pp. 1-14, 1983.
55. Melchers, F., Corbel, C.: Lymphocyte cooperations in the immune response and the immune defence against bacteria. In: "Bacterial and Viral Inhibition and Modulation of Host Defences", eds. G. Falcone, M. Campa, H. Smith, G.M. Scott, pp. 111-117, Academic Press, London, 1984.
56. Melchers, F., Morse, H.C., Potter, M., Shapiro, M., Weigert, M.: Mechanisms in B-cell neoplasia. Immunol. Today 5:213-117, 1984.
57. Lernhardt, W., Corbel, C., Melchers, F., Wall, R.: Functional and molecular characterization of murine B cell replication factor derived from a T cell hybridoma. In: "Regulation of the Immune System", New Series Vol. 18, eds. H. Cantor, L. Chess, E. Sercarz, pp. 573-581, Alan R. Liss, Inc., New York, 1984.
58. Melchers, F.: Introduction. In: "Basel Institute for Immunology Annual Report 1983", Basel Institute for Immunology, pp. 1-12, 1984.
59. Melchers, F., Andersson, J.: B cell activation: Three steps and their variations. Cell 37:715-720, 1984.
60. Corbel, C., Leptin, M., Melchers, F.: The roles of immunoglobulin M H-chain-specific monoclonal antibodies, of lipopolysaccharide, and of dextransulfate or agar mitogen in murine B cell stimulation. In: "Lymphokines", Vol. 10, eds. M.H. Schreier, K.A. Smith, pp. 109-126, Academic Press, New York, 1985.
61. Melchers, F.: Die Erkennung von Antigenen und die Antwort des Immunsystems - eine Kooperation verschiedener Zellen des Systems. In: "Verhandlungen der Gesellschaft Deutscher Naturforscher und Aerzte, 113. Versammlung, Nürnberg 1984", eds. P. Karlson, G. Bettendorf, H. Marko, W. Sachsenmaier, D. Schneider, H.A. Staab, H. Gibian, pp. 347-357, Wissenschaftliche Verlagsgesellschaft mbH, Stuttgart, 1985.
62. Melchers, F.: Cellular and molecular requirements for B cell activation. In: "Immunopharmacology", Vol. 23 Seron Symp. Publications, eds. P.A. Miescher, L. Bolis, M. Ghione, pp. 9-12, Raven Press, New York, 1985.
63. Melchers, F., Corbel, C., Leptin, M., Lernhardt, W.: Activation and cell cycle control of murine B-lymphocytes, J. Cell Sci., Suppl. 3, pp. 77-82, 1985.
64. Melchers, F.: Introduction. In: "Basel Institute for Immunology Annual Report 1984", Basel Institute for Immunology, pp. 9-22, 1985.
65. Melchers, F., Corbel, C., Leptin, M., Lernhardt, W.: Activation and cell cycle control of murine B lymphocytes. J. Cell Sci. Suppl. 3:77-82, 1985.
66. Marcu, K., Melchers, F., Morse III, H.C., Potter, M.: Mechanisms in B-cell neoplasia. Immunol. Today 7:249-253, 1986.
67. Melchers, F.: Regulation of B cell responses.In: "Recent Advances in Primary and Acquired Immunodeficiencies", eds. F. Aiuti, F. Rosen, M.D. Cooper, pp. 31-35, Raven Press, New York, 1986.
68. Melchers, F.: Murine B cell cycle control and its deregulations in NZW, NZB and BXSB mice. In: "Primary Immunodeficiency Diseases", eds. M.M. Eibl, F.S. Rosen, pp. 71-76, Elsevier Science Publishers B.V., Amsterdam, 1986.
69. Melchers, F., Andersson, J.: Factors controlling the B-cell cycle. Ann. Rev. Immunol. 4:13-36, 1986.
70. Marcu, K., Melchers, F., Morse III, H.C., Potter, M.: Mechanisms in B-cell neoplasia. Immunol. Today 7:249-253, 1986.
71. Melchers, F.: Regulation of B cell responses.In: "Recent Advances in Primary and Acquired Immunodeficiencies", eds. F. Aiuti, F. Rosen, M.D. Cooper, pp. 31-35, Raven Press, New York, 1986.
72. Melchers, F., Erdei, A., Corbel, C., Leptin, M., Schulz, T., Dierich, M.P.: Cell cycle control of activated, synchronized murine B lymphocytes - roles of macrophages and complement C3. Mol. Immunol. 23:1173-1176, 1986.
73. Melchers, F.: Regulation of the cell cycle of murine B lymphocytes bylipopolysaccharides. In: "Immunobiology and Immunopharmacology of Bacterial Endotoxins", eds. A. Szentivanyi, H. Friedman, A. Nowotny, pp. 301-304, Plenum Press, New York, 1986.
74. Melchers, F.: Introduction. In: "Basel Institute for Immunology Annual Report 1985", Basel Institute for Immunology, pp. 9-28, 1986.
75. Melchers, F.: Control of the mitotic B cell cycle - facts and speculations. In: "The Molecular Basis of B-Cell Differentiation and Function", Vol 123, eds. M. Ferrarini, B. Pernis, pp. 49-57, Plenum Press, New York, 1986.
76. Melchers, F.:Control of B cell proliferation. In: "AIDS Research and Human Retroviruses", Vol. 3, Suppl. 1, pp. 219-223, 1987.
77. Melchers, F.: Die Vererbung des Reichtums der Erkennung, Neue Zürcher Zeitung 262:65, 1987.
78. Melchers, F.:Protein-A plaque assay. In: "Methods in Enzymology", vol. 15, ed. G. Di Sabato, pp.217-222, Academic Press, San Diego, 1987.
79. Melchers, F.: Introduction. In: "Basel Institute for Immunology Annual Report 1986", Basel Institute for Immunology, pp. 8-19, 1987.
80. Rolink, A.G., Andersson, J., Karasuyama, H., Melchers, F.: The effects of IL-2 to 6 on the maturation and proliferation of mouse B cells. In: Proc. 9th Europ. Immunology Meetings, Rome, 1988.
81. Lernhardt, W., Melchers, F.: The role of C3 and its fragments in the control of S phase entry of activated mouse B lymphocytes via the complement receptor type 2. Exp. Clin. Immunogenet. 5:115-122, 1988.
82. Melchers, F.: Introduction. In: "Basel Institute for Immunology Annual Report 1987", Basel Institute for Immunology, pp. 8-22, 1988.
83. Melchers, F. Auf der Suche nach dem Immunsystem. In: Forschung bei Roche/Research at Roche, eds. J. Drews, F. Melchers, pp. 179-196, Editiones Roche, Basel, 1989.
84. Rolink, A., Streb, M., Karasuyama, H., Melchers, F.: Cell-cell contact- and cytokine-controlled B lymphocyte responses and their potential influences in hematopoiesis.Adv. Immunopharmacol. 4:73-80, 1989.
85. Melchers, F.: Pleiotropism and pleiomorphism of cytokines-immunostimulated and endogenous ways of hematopoiesis?In: "Molecular and Cellular Networks for Cancer Therapy", eds. Y. Yamamura, I. Azuma, Excerpta Medica, pp. 3-11, Amsterdam, Princeton, Hong Kong, Tokyo, Sydney, 1989.
86. Melchers, F.: The many roles of immunoglobulin molecules in the development and growth control of the B lymphocyte lineage. In: "Immunoglobulin Genes", eds. T. Honjo, F.W. Alt, T. Rabbits, pp. 23-44, Academic Press, New York, 1989.
87. Melchers, F.:The development of the scientific program of the 7th International Congress of Immunology. Immunol. Today 10:53-55, 1989.
88. Melchers, F:Opening speech.In: "Progress in Immunology VII, Proceedings of the 7th International Congress of Immunology, Berlin: 1989", eds. F. Melchers et al., pp. XXX-XXXII, Springer-Verlag, Berlin, 1989.
89. Melchers, F., Bauer, S.R., Berger, C., Karasuyama, H., Kudo, A., Rolink, A., Sakaguchi, N., Strasser, A., Thalmann, P.:Precursor B lymphocyte-specific monoclonal antibodies and genes.In: "Mechanisms of Lymphocyte Activation and Immune Regulation II", eds. S. Gupta, W.E. Paul, pp. 87-93, Plenum Press, New York, 1989.
90. Rolink, A., Streb, M., Karasuyama, H., Melchers, F.:Cell-cell contact- and cytokine-controlled B lymphocyte responses and their potential influences in hematopoiesis. Adv. Immunopharmacol. 4:73-80, 1989.
91. Melchers, F.: Introduction. In: "Basel Institute for Immunology Annual Report 1988", Basel Institute for Immunology, pp. 10-23, 1989.
92. Melchers, F., Strasser, A., Bauer, S.R., Kudo, A., Thalmann, P., Rolink, A.:Cellular stages and molecular steps of murine B-cell development. Cold Spring Harbor Symp. Quant. Biol. 54:183-189, 1989.
93. Melchers, F., Bauer, S.R., Berger, C., Karasuyama, H., Kudo, A., Sakaguchi, N., Strasser, A., Thalmann, P.: Precursor B lymphocyte-specific monoclonal antibodies and genes. In: “Mechanisms of Lymphocyte Activation and Immune Regulation II”, eds. S. Gupta, W.E. Paul, pp. 87-93, Plenum Press, New York, 1989.
94. Rolink, A.G., Strasser, A., Melchers, F.: Autoimmune diseases induced by graft-versus-host reaction. In: "Graft Vs. Host Disease", eds. S. Burakoff, A. Deeg, J. Ferrara, B. Atkinson, pp. 161-175, M. Dekker Publ., New York, 1990.
95. Melchers, F.: Introduction. In: "Basel Institute for Immunology Annual Report 1989", Basel Institute for Immunology, pp. 10-21, 1990.
96. Melchers, F.:Cell to cell cooperations in B cell development and B cell responses.In: "Cell to Cell Interaction", eds. M.M. Burger, B. Sordat, R.M. Zinkernagel, S. Karger, Basel, 1990.
97. Melchers, F.:Potential und Perspektiven der Immunologie im Jahr 1990. Deutsche Medizinische Wochenschrift 115:1887-1893, 1990.
98. Melchers, F.:Segen und Fluch des Immunsystems.Ges. Deutsche Naturforscher und Aerzte 116:357-373, 1990.
99. Melchers, F.:Antigenicity, immunogenicity and tolerogenicity of idiotypes in an immune system with three classes of receptors: problems of a functional network.In: “Idiotype Networks in Biology and Medicine”, eds. A.D.M.E. Osterhaus, F.G.C.M. UytdeHaag, pp. 3-12, Elsevier Science Publishers B.V., Amsterdam, 1990.
100. Melchers, F.: Molecular Immunology: Introduction. In: "Influence of molecular biology on drug discovery". Roche Symposium Tokyo April 1989, eds. K. Udaka, Y. Furuichi, J. Drews, pp. 3-4, Zuckschwerdt Verlag, München, 1990.
101. Melchers, F.:Immunity and autoimmunity: with special reference to inner ear diseases. Adv. Oto-Rhino-Laryngol. 46:17-25, 1991.
102. Melchers, F., Strasser, A., Bauer, S.R., Kudo, A., Thalmann, P., Rolink, A.:B cell development in fetal liver.In: "Mechanisms of Lymphocyte Activation and Immunoregulation III", eds. S. Gupta et al., pp. 201-205, Plenum Press, New York, 1991.
103. Melchers, F.: The Basel Institute for Immunology. In: "Conference on High Technology and Society", ed. A. Scheinin, pp. 35-41, Foundation of new Technology, Turku, 1991.
104. Rolink, A., Melchers, F.Molecular and cellular origins of B lymphocyte diversity., Cell 66:1081-1094, 1991.
105. Melchers, F.: Introduction. In: "Basel Institute for Immunology Annual Report 1990", Basel Institute for Immunology, pp. 8-21, 1991.
106. Melchers, F.: Immunity and autoimmunity. With special reference to inner ear diseases. In: “Advances in Oto-Rhino-Laryngology”, Vol. 46, eds. C.R. Pfaltz et al., pp. 17-25, Karger, Basel, 1991.
107. Lasilla, O., Vainio, O., Toivanen, P. Melchers, F.: Doing the B-cell Rag. New Biologist 3:1-6, 1991.
108. Melchers, F.: Introduction. In: "Basel Institute for Immunology Annual Report 1991", Basel Institute for Immunology, pp. 8-22, 1992.
109. Melchers, F.: Erkennen, Erlernen und Erinnern im Immunsystem. Nova Acta Leopoldina 67:251-265, 1992.
110. Melchers, F., Haasner, D., Karasuyama, H., Reininger, L., Rolink, A.: Progenitor and precursor B lymphocytes of mice.Proliferation and differentiation in vitro and population, differentiation and turnover in SCID mice in vivo of normal and abnormal cells. Curr. Top. Microbiol. Immunol. 182:3-12, 1992.
111. Melchers, F.: Antibodies, synthesis. In: “Encyclopaedia of Immunology”, Vol. 1, eds. I.M. Roitt, P.J. Delves, pp. 94-96, Academic Press, London, 1992.
112. Melchers, F., Haasner, D., Streb, M., Rolink, A.: B-lymphocyte lineage-committed, IL-7 and stroma cell-reactive progenitors and precursors, and their differentiation to B cells. In: “Mechanisms of Lymphocyte Activation and Immune Regulation IV: Cellular Communications’’, eds. S. Gupta, T.A. Waldmann, pp. 111-117, Plenum Press, New York, 1992.
113. Melchers, F., Karasuyama, H., Haasner, D., Rolink, A.: Birth, life and death of a B cell. In: “Progress in Immunology VIII. Proceedings of the 8th International Congress for Immunology, Budapest”, eds. J. Gergely et al., pp.11-19, Springer-Verlag, Budapest, 1992.
114. Melchers, F., Karasuyama, H., Haasner, D., Bauer, S., Kudo, A., Sakaguchi, N., Jameson, B., Rolink, A.: The surrogate light chain in B-cell development.Immunol. Today 14:60-68, 1993.
115. Melchers, F.: Introduction. In: "Basel Institute for Immunology Annual Report 1992", Basel Institute for Immunology, pp. 10-25, 1993.
116. Rolink, A., Melchers, F.: B lymphopoiesis in the mouse. Adv. in Immunol. 53:123-155, Academic Press, Orlando, 1993.
117. Melchers, F.:The dominance of antigen-specific receptors in antigen-specific immune responses.Curr. Top. Microbiol. Immunol.184:1-3, 1993.
118. Rolink, A., Melchers, F.: Generation and regeneration of cells of the B-lymphocyte lineage. Curr. Opin. Immunol. 5:207-217, 1993.
119. Melchers, F., Grawunder, U., Haasner, D., Karasuyama, H., Reininger, L., Rolink, A.: B cell development in the mouse: Scenarios for defects expressed in the B cell lineage. Proc. Symp. in Immunology, Humoral Immunodeficiencies, Lucca Italy, 1993.
120. Melchers, F., Haasner, D., Grawunder, U., Kalberer, C., Karasuyama, H., Winkler, T., Rolink, A.: Roles of IgH and L chains and of surrogate H and L chains in the development of cells of the B lymphocyte lineage. Ann. Rev. Immunol. 12:209-225, 1994.
121. Melchers, F.: Introduction. In: "Basel Institute for Immunology Annual Report 1993”, Basel Institute for Immunology, pp. 10-25, 1994.
122. Rolink, A., Karasuyama, H., Haasner, D., Grawunder, U., Mårtensson, I.-L., Kudo, A., Melchers, F.: Two pathways of B lymphocyte development in mouse bone marrow and the roles of surrogate L chain in this development.In: “Immunol. Reviews”, ed. G Möller, pp. 185-201, Munksgaard Intl Pub Ltd, Copenhagen, 1994.
123. Melchers, F.,: The role of B cell and pre-B-cell receptors in development and growth control of the B-lymphocyte cell lineage. In “Immunoglobulin Genes” (vol. 2), eds. F.W. Alt, T. Honjo, pp. 36-56, Academic Press, San Diego, 1995.
124. Melchers, F.: Introduction. In: “Basel Institute for Immunology Annual Report 1994”, Basel Institute for Immunology, pp. 16-34, 1995.
125. Rolink, A., Andersson, J., Ghia, P., Grawunder, U., Haasner, D., Karasuyama, H., ten Boekel, E., Winkler, T.H., Melchers, F.: B cell development in mouse and man. Immunologist 3/4:125-151, 1995.
126. Melchers, F., Shortman, K.:Lymphocyte development. Curr. Opin. Immunol. 7:173-175, 1995.
127. Melchers, F., Rolink, A., Grawunder, U., Winkler, T.H., Karasuyama, H., Ghia, P., Andersson, J.: Positive and negative selection events during B lympho¬poiesis. Curr. Opin. Immunol. 7:214-227, 1995.
128. Melchers, F.: Developmental biology of lymphocytes. Res. Immunol. 146, 1995.
129. Melchers, F.:B cell differentiation in bone marrow. Clin. Immunol & Immunopathol. 76:S188-S191, 1995.
130. Melchers, F.: Introduction. In: “Basel Institute for Immunology Annual Report 1995”, Basel Institute for Immunology, pp. 12-28, 1996.
131. Rolink, A., Haasner, D., Melchers, F., Andersson, J.:The surrogate light chain in mouse B-cell development. Int. Rev. Immunol. 13:341-356, 1996.
132. Karasuyama, H., Rolink, A., Melchers, F.: Surrogate light chain in B cell development. Adv. in Immunol. 63:1-41, 1996.
133. Rolink, A., Melchers, F. “In vitro” growth and differentiation of early mouse B cell precursors. In: “Immunology Methods Manual: The Comprehensive Sourcebook of Techniques, vol. 2, I. Lefkovits, ed., p. 959-963. Academic Press, San Diego, 1997.
134. Rolink, A., Melchers, F. Outlook. In: Immunology Methods Manual: The comprehensive Sourcebook of Techniques, vol. 2, I. Lefkovits, ed., p. 969-971. Academic Press, San Diego, 1997.
135. Melchers, F.: Introduction. In: "Basel Institute for Immunology Annual Report 1996”, Basel Institute for Immunology, pp. 17-32, 1997.
136. Melchers, F. B-lymphocyte-lineage cells from early precursors to Ig-secreting plasma cells: targets of regulation by the myc/mad/max families of genes? In: Curr. Top. Microbiol. Immunol. 224:19-30, 1997.
137. Siwarski, D., Müller, U., Andersson, J., Notario, V., Melchers, F., Rolink, A., Huppi, K. Structure and expression of the c-Myc/Pv11 megagene locus. Curr. Top. Microbiol. Immunol. 224:67-72, 1997.
138. Melchers, F.:Biographical Memoirs: Niels Kaj Jerne. Proc. Amer. Philosoph. Soc. 141:89-96, 1997.
139. Melchers, F.: Lymphoid development. In: "Molecular and cellular components of the immune system". Summary of sessions at ENII Conference, Les Embiez 1997. Res. Immunol. 148:426-428, 1997.
140. Melchers, F.: The development of lymphocytes. (The Karl Prausnitz Memorial Lecture). Int. Arch. Allergy Immunol. 113:11-13, 1997.
141. Melchers, F.: Introduction. In: "Basel Institute for Immunology Annual Report 1997”, Basel Institute for Immunology, pp. 1-17, 1998.
142. Winkler, T.H., Melchers, F. Structure and Function of the Pro- and Pre-B-Cell Receptors on B`Lymphoid Lineage Precursor Cells. In: B and T Cell Development. In: Molecular Biology of B and T Cell development, eds. J. G. Monroe, E. Rothenberg. Humana Press Inc., Totowa, N.J. USA, Chapter 20, 399-420, 1998.
143. Melchers, F. Lymphocyte Development. In: Immunological Defences, Frontiere della vita, Enciclopedia Italiana, vol. 6, ed. A. Turchi. Rome, 1998.
144. Melchers, F.: Antibodies, synthesis. In: “Encyclopaedia of Immunology”, 2nd edition, eds. I.M. Roitt, P.J. Delves, pp. 154-158, Academic Press, 1998.
145. Melchers, F. ten Boekel, E., Yamagama, T., Seidl, T., Ceredig, R., Rolink A.G., Andersson J. Generation of B-cell repertoire. In: The International Symposium on Immunoglobulin Genes and B Lymphocytes, Honjo, T., ed., Org. Comm., Kyoto, Japan, pp. 31-35, 1998.
146. Melchers, F. In: "1967-1997 – 30 Jahre Deutsche Gesellschaft für Immunologie,Immunologische Forschung in Deutschland 1967-1997". pp. 14-121, 1998.
147. Melchers, F.: Introduction. In: "Basel Institute for Immunology Annual Report 1998”, Basel Institute for Immunology, pp. 1-17, 1999.
148. Rolink, R., Andersson, J., Ghia, P., Grawunder, U., Kalberer, C., Karasuyama, H., Oka, Y., ten Boekel, E., Winkler, T., Melchers F. Molecular mechanisms guiding B cell development. In: “Primary Immunodeficiency Diseases, a Molecular and Genetic Approach”,eds. Ochs, H., Smith, E., Puck, J. pp. 55-65, 1999.
149. Rolink, A.G., ten Boekel, E., Yamagami, T., Ceredig, R., Andersson, J. Melchers, F.B cell development in the mouse from early progenitors to mature B cells. Immunol. Lett. 68:89-93, 1999.
150. Melchers, F., Rolink, A.G. B lymphocyte development and biology. In: Fundamental Immunology, 4th ed., Paul, W.H. ed., Lippincott-Raven Publishers, Philadelphia, pp. 183-224, 1999.
151. Melchers, F. Commentary: Fit for life in the immune system? – Surrogate L chain tests H chains which test L chains. Proc.Natl. Acad. Sci. USA, 96:2571-2573, 1999.
152. ten Boekel E, Yamagami T, Andersson J, Rolink AG, Melchers F. The formation and selection of cells expressing preB cell receptors and B cell receptors. Curr. Top. Microbiol. Immunol. 246:3-9, 1999.
153. Ceredig R, Rolink AG, Melchers F, Andersson J. Fetal liver organ cultures as a tool to study selection processes during B cell development. Curr. Top. Microbiol. Immunol. 246:11-17, 1999.
154. Rolink AG, Melchers F, Andersson J. The transition from immature to mature B cells. Curr. Top. Microbiol. Immunol. 246:39-43, 1999.
155. Schaniel, C., Sallusto, F., Sideras, P, Melchers, F., Rolink,A.G. A novel CC chemokine ABCD-1, produced by dendritic cells and activated B cells, exclusively attracts activated T lympho¬cytes. Curr. Top. Microbiol. Immunol. 246:95-101, 1999.
156. Melchers, F., Rolink, A.G., Schaniel, C. The role of chemokines in regulating cell migration during humoral immune responses. (Minireview), Cell, 99:351-354, 1999.
157. Melchers, F. Differentiation, Dedifferentiation and Redifferentiation of B-lineage Lymphocytes: Roles of the Surrogate Light Chain and the Pax5 Gene. In: Cold Spring Harbor Symp. on Quantitative Biology, vol. LXIV, Cold Spring Harbor Laboratory Press, pp. 21-25, 1999.
158. Melchers, F., ten Boekel, E., Yamagami, T., Andersson, J., Rolink A. The roles of preB and B cell receptors in the stepwise allelic exclusion of mouse IgH and L chain gene loci. Seminars in Immunology, 11:307-319, 1999.
159. Ceredig, R., A. G. Rolink, et al. (2000). The B cell receptor, but not the pre-B cell receptor, mediates arrest of B cell differentiation. Eur J Immunol 30(3): 759-67.
160. Ghia P, Melchers F, Rolink AG. Age-dependent changes in B lymphocyte development in man and mouse. Exp Gerontol 35:159-165, 2000.
161. Melchers, F.: Introduction. In: "Basel Institute for Immunology Annual Report 1999”, Basel Institute for Immunology, pp. 3-22, 2000.
162. Melchers, F., ten Boekel, E., Seidl, T., Kong, X.C., Yamagami, T., Ohnishi, K., Shimizu, T., Rolink, A.G., Andersson, J. Repertoire selection by pre-B-cell receptors and B-cell receptors, and genetic control of B-cell development from immature to mature B cells. Immunol Rev 175:33-46, 2000.
163.Melchers, F., Rolink, A., Hematopoietic stem cells - the problem of commitment versus plasticity. In: Stem Cells, Cold Spring Harbor Laboratory Press (2000)
164.Ogawa, M., E. ten Boekel, Melchers, F. et al. (2000). Identification of CD19(-)B220(+)c-Kit(+)Flt3/Flk-2(+)cells as early B lymphoid precursors before pre-B-I cells in juvenile mouse bone marrow. Int Immunol 12(3): 313-24.
165.Ohnishi, K., T. Shimizu, Melchers, F. et al. (2000). The identification of a nonclassical cadherin expressed during B cell development and its interaction with surrogate light chain. J Biol Chem 275(40):31134-44.
166. Potter, M. and F. Melchers (2000). Opinions on the nature of B-1 cells and their relationship to B cell neoplasia. Curr Top Microbiol Immunol 252: 307-24.
167. Rolink, A.G., Schaniel, Ch., Busslinger, M., Nutt, S.L., Melchers, F. Fidelity and infidelity in commitment to B-lymphocyte lineage development. Immunol Rev 175:104-111, 2000.
168. Rolink A.G., Melchers F. Precursor B cells from Pax-5-deficient mice – stem cells for macrophages, granulocytes, osteoclasts, dendritic cells, natural killer cells, thymocytes and T cells. Curr. Top. Micro. Immunol. 251:21-26, 2000.
169.Rolink, A. G., T. Winkler, Melchers, F. et al. (2000). PrecursorB cell receptor-dependent B cell proliferation and differentiation does not require the bone marrow or fetal liver environment. J Exp Med 191(1): 23-32.
170. Schaniel, C., Melchers, F., Rolink, A.G. The cluster of ABCD chemokines which organizes T cell-dependent B cell responses. Curr. Top. Micro. Immunol. 251:181-189, 2000.
171. Hess, J., A. Werner, Melchers, F. et al. (2001). Induction of pre-B cell proliferation after de novo synthesis of the pre-B cell receptor. Proc Natl Acad Sci U S A 98(4): 1745-50.
172. Mundt, C., S. Licence, Melchers F. et al. (2001). Loss of precursor B cell expansion but notallelic exclusion in VpreB1/VpreB2 double-deficient mice. J Exp Med 193(4): 435-45.
173. Raulet, D.H. and Melchers, F.: Lymphocyte development. Editorial overview. Curr. Opin. Immunol. 13:163-165, 2001.
174. Rolink, A. G., C. Schaniel, Melchers F. et al. (2001). Selection events operating at various stages in B cell development. Curr Opin Immunol 13(2): 202-7.
175.Schaniel, C., A. G. Rolink, Melchers F. et al. (2001). Attractions and migrations of lymphoid cells in the organization of humoral immune responses.Adv Immunol 78: 111-68.
176.Seidl, T., A. Rolink, Melchers F. et al. (2001). The VpreB protein of the surrogate light-chain can pair with some mu heavy-chains in the absence of the lambda 5 protein. Eur J Immunol 31(7): 1999-2006.
177. Hoffmann, R., T. Seidl, Melchers F. et al. (2002). Changes in gene expression profiles in developing B cells of murine bone marrow. Genome Res 12(1): 98-111.
178.Martensson, I. L., A. Rolink, Melchers F. et al. (2002). The pre-B cell receptor and its role in proliferation and Ig heavy chain allelic exclusion. Semin Immunol 14(5): 335-42.
179. Rolink, A. G., C. Schaniel, Melchers F. et al. (2002). Stability and plasticity of wild-typeand Pax5-deficient precursor B cells. Immunol Rev 187: 87-95.
180.Rolink, A. G., J. Tschopp, Melchers F. et al. (2002). BAFF is a survival and maturation factor for mouse B cells. Eur J Immunol 32(7): 2004-10.
181.Rolink, A. G., C. Schaniel, Melchers F. et al. (2002). In vitro and in vivo plasticity of Pax5-deficient pre-B I cells. Immunol Lett 82(1-2): 35-40.
182.Rolink, A. G. and F. Melchers (2002). BAFFled B cells survive and thrive: roles of BAFF in B-cell development. Curr Opin Immunol 14(2): 266-75.
183.Schaniel, C., M. Gottar, Melchers F. et al. (2002). Extensive in vivo self-renewal, long-term reconstitution capacity, and hematopoietic multipotency of Pax5-deficient precursor B-cell clones. Blood 99(8): 2760-6.
184. Schaniel, C., L. Bruno, Melchers F. et al. (2002). Multiple hematopoietic cell lineages develop in vivo from transplanted Pax5-deficient pre-B I-cell clones. Blood 99(2): 472-8.
185. Shimizu, T., C. Mundt, Melchers F. et al. (2002). VpreB1/VpreB2/lambda 5 triple-deficient mice show impaired B cell development but functional allelic exclusion of the IgH locus. J Immunol 168(12): 6286-93.
186.Felix, K., A. Rolink, Melchers F. et al. (2003). Bcl-2 reduces mutant rates in a transgenic lacZ reporter gene in mouse pre-B lymphocytes. Mutat Res 522(1-2): 135-44.
187.Hoffmann, R. and F. Melchers (2003). A genomicview of lymphocyte development. Curr Opin Immunol 15(3): 239-45.
188.Hoffmann, R., L. Bruno, Melchers F. et al. (2003). Rules for gene usage inferred from a comparison of large-scale gene expression profiles of T and B lymphocyte development. J Immunol 170(3): 1339-53.
189.Li, H., Y. Oka, Melchers F. et al. (2003). The lck promoter-driven expression of the Wilms tumor gene WT1 blocks intrathymic differentiation of T-lineage cells. Int J Hematol 77(5): 463-70.
190. Ohnishi, K. and F. Melchers (2003). The nonimmunoglobulin portion of lambda5 mediates cell-autonomous pre-B cell receptor signaling. Nat Immunol 4(9): 849-56.
191.Melchers, F. (2004). The death of a dogma? Nat Immunol 5(12): 1199-201.
192. Rolink, A. G., J. Andersson, Melchers F. et al. (2004). Molecular mechanisms guiding late stages of B-cell development. Immunol Rev 197: 41-50.
193.Ardouin, L., A. G. Rolink, Melchers F. et al. (2005). Rapid in vivo analysis of mutant forms of the LAT adaptor using Pax5-Lat double-deficient pro-B cells. Eur J Immunol 35(3): 977-86.
194. Ohnishi, K., F. Melchers, et al. (2005). Lymphocyte-expressed BILL-cadherin/cadherin-17 contributes to the development of B cells at two stages. Eur J Immunol 35(3): 957-63.
Books edited
1. The Immune System. 27th Colloquium der Gesellschaft für Biologische Chemie, Mosbach, 1976, eds. F. Melchers and K. Rajewsky, Springer Verlag, Berlin, Heidelberg, New York, 1976.
2. Lymphocyte Hybridomas. Curr. Top. Microbiol. Immunol. 81, eds. F. Melchers, M. Potter, and N.L. Warner, Springer Verlag, Berlin, Heidelberg, New York, 1978.
3. T Cell Hybridomas. Curr. Top. Microbiol. Immunol. 100, eds. H. v. Boehmer, W. Haas, G. Köhler, F. Melchers, and J. Zeuthen, Springer Verlag, Berlin, Heidelberg, New York, 1982.
4. Mechanisms of B Cell Neoplasia. eds. F. Melchers, M. Potter, and M. Weigert, Editiones Roche, Basel, 1983.
5. Oncogenes in B Cell Neoplasia. Curr. Top. Microbiol. Immunol. 113, eds. M. Potter, F. Melchers, and M. Weigert, Springer Verlag, Berlin, Heidelberg, New York, 1984.
6. Images of Biologically Active Structures in the Immune System. Curr. Top. Microbiol. Immunol. 119, eds. H. Koprowski and F. Melchers, Springer Verlag, Berlin, Heidelberg, New York, 1985.
7. Mechanisms of B Cell Neoplasia. eds. F. Melchers and M. Potter, Editiones Roche, Basel, 1985.
8. Peptides as Immunogens. Curr. Top. Microbiol. Immunol. 130, eds. H. Koprowski and F. Melchers, Springer Verlag, Berlin, Heidelberg, New York, 1986.
9. Mechanisms in B-Cell Neoplasia. Curr. Top. Microbiol. Immunol. 132, eds. F. Melchers and M. Potter, Springer Verlag, Berlin, Heidelberg, New York, 1986.
10. Mechanisms of B Cell Neoplasia. eds. F. Melchers and M. Potter, Editiones Roche, Basel, 1987.
11. Mechanisms in B-Cell Neoplasia 1988. Curr. Top. Microbiol. Immunol. 141, Springer Verlag, Berlin, Heidelberg, New York, 1988.
12. Forschung bei Roche/Research at Roche. eds. J. Drews and F. Melchers, Editiones Roche, Basel, 1989.
13. Progress in Immunology, Volume 7.Proceedings of the 7th International Congress of Immunology, 1989, Berlin, eds. F. Melchers et al., Springer Verlag, Berlin, Heidelberg, New York, Tokyo, 1989.
14. Mechanisms of B Cell Neoplasia. eds. F. Melchers and M. Potter, Editiones Roche, Basel, 1989.
15. Mechanisms of B Cell Neoplasia 1990, Curr. Top. Microbiol. Immunol. 166, eds. M. Potter and F. Melchers, Springer Verlag, Berlin, Heidelberg, New York , 1990.
16. Mechanisms of B Cell Neoplasia. eds. F. Melchers and M. Potter, Editiones Roche, Basel, 1991.
17. Mechanisms of B Cell Neoplasia 1992, Curr. Top. Microbiol. Immunol., eds. M. Potter and F. Melchers, Springer Verlag, Berlin, Heidelberg, New York , 1992.
18. Mechanisms of B Cell Neoplasia. eds. F. Melchers and M. Potter, Editiones Roche, Basel, 1993.
19. Mechanisms in B-Cell Neoplasia 1994, Curr. Top. Microbiol. Immunol., eds. M. Potter and F. Melchers, Springer Verlag, Berlin, Heidelberg, New York, 1995.
20. Mechanisms of B Cell Neoplasia 1995, eds. M. Potter and F. Melchers, Editiones Roche, Basel, 1996.
21. C-Myc in B-Cell Neoplasia 1996, Curr. Top. Micro biol. Immunol., eds. M. Potter and F. Melchers, Springer Verlag, Berlin, Heidelberg, New York, 1997.
22. Mechanisms of B Cell Neoplasia 1998, Curr. Top. Microbiol. Immunol. 246, eds. F. Melchers and M. Potter, Springer Verlag, Berlin, Heidelberg, New York, 1999.
23. Lymphoid Organogenesis, Curr. Top. Microbiol. Immunol. 251, ed. F. Melchers, Springer Verlag, Berlin, Heidelberg, New York, 2000.
24. Mechanisms of B-Cell Neoplasia 1999, Curr. Top. Microbiol. Immunol. 252, eds. F. Melchers and Potter, M., Springer Verlag Berlin, Heidelberg, New York, 2000.